2026-04-23
The effect of IL-1 blockers on exertional leg pain in familial Mediterranean fever patients: an exploratory study
What was examined: CONCLUSION: IL-1 blockers provide meaningful benefit in approximately half of patients with FMF-related ELP, supporting their role as a therapeutic option for this refractory manifestation. However, the persistence of ELP in a substantial proportion of patients underscores the need for additional therapeutic strategies to address this disabling manifestation.
Insight: open the full study on PubMed for complete details.
2025-10-01
Acute Attack Treatment: Fast Anakinra Injection
What was examined: whether a single Kineret injection can stop an FMF attack.
Patient insight: a timely single Anakinra (Kineret) injection can stop the attack and significantly reduce pain and duration.
2025-10-01
Characteristics of Patients With Double V694M Mutations
What was examined: the health impact of double V694M mutation carriage.
Insight: homozygous patients have higher risk for severe disease, colchicine non-response, and complications; close monitoring is required.
2025-07-01
Plaquenil in Cutaneous Lupus
What was examined: whether early treatment prevents systemic lupus.
Insight: early treatment reduces risk of progression to systemic lupus.
2025-05-01
JAK Inhibitors and Risk of Intestinal Perforation
What was examined: whether there is risk for intestinal perforation.
Insight: increased reporting was found; in patients at risk for diverticular disease, treatment should be considered with caution.
2025-04-01
Follow-up of FMF Patients With Amyloidosis
What was examined: whether low renal function at diagnosis predicts kidney failure.
Insight: early detection and blood/urine follow-up are important to prevent kidney failure.
